MOTS-c is a peptide encoded inside mitochondrial DNA, studied as an exercise-mimetic signal tied to energy use and insulin sensitivity. The research is preclinical; human trials are just beginning. Community protocols commonly report 2.5 mg per injection, two to three times weekly — and the sources that quote 5–10 mg are quoting weekly totals, so reading them as a single injection doubles or quadruples the draw. Those are reported figures, not recommendations. The 10 mg vial has to be dissolved in bacteriostatic water before anything can be measured, and because the reported amount is large, the water volume changes the draw considerably. The table and calculator below do that arithmetic.
Open the MOTS-c calculator →| Concentration | 1 mL water | 2 mL water | 3 mL water | 5 mL water |
|---|---|---|---|---|
| 10 mg vial | 10,000 mcg/mL | 5,000 mcg/mL | 3,333 mcg/mL | 2,000 mcg/mL |
Concentration = vial contents ÷ water added. It is the same compound at every volume — more water only means a weaker solution, larger syringe marks that are easier to read, and a larger injection volume. On a standard U-100 insulin syringe, one unit is 0.01 mL at any barrel size.
Calculate a MOTS-c draw →Education only. This page is educational. Most compounds referenced are not approved for human use, and a "research use only" label carries no legal status of its own.
Arithmetic, not advice. The calculator performs unit-conversion arithmetic on figures you enter. It does not recommend a dose, a quantity, or a method of administration.
Reference ranges. Any amounts mentioned are values commonly reported in published research and community protocols, provided for reference only. Reported does not mean established, safe, or effective.
Not medical advice. Nothing here constitutes medical advice, diagnosis, or treatment. Consult a qualified healthcare professional before beginning any protocol.