For education only · Not medical advice
Reference · Most popular

2026's most popular peptides.

What each one is studied for, and what people actually use it for. We stopped averaging community dosing — too many variables, too easy to imply more certainty than exists. Where you see a dose below, it's drawn from real personal experience; everywhere else, that field is left blank on purpose rather than filled with a guess.

What each one is · what it's used for
01BPC-157Recovery
What people use it for

Accelerated healing of tendons, ligaments, muscle, and joint injuries; reduced chronic pain and inflammation; improvements in gut issues (IBS, ulcers, digestive comfort).

Researched for

Tissue repair across tendon, ligament and gut models. One of the most-studied compounds in the field — but nearly all of it in animals.

An average dose looks like:

10 mg vial + 2 mL water = 5,000 mcg/mL
500 mcg → 0.10 mL  ·  10 units

Read the deep dive →

See the full profile →

02TB-500Recovery
What people use it for

Accelerated soft-tissue healing (tendons, ligaments, muscles); reduced inflammation and joint pain; improved flexibility and range of motion; faster recovery between workouts.

Researched for

The research form of thymosin β-4 — wound healing, blood-vessel formation and tissue remodelling.

An average dose looks like:

10 mg vial + 2 mL water = 5,000 mcg/mL
1 mg → 0.20 mL  ·  20 units

Read the deep dive →

See the full profile →

03KLOWRecovery & skin
What people use it for

One injection covering skin quality, tissue repair, and gut/systemic inflammation at once, instead of running four separate peptides.

Researched for

A four-peptide blend — GHK-Cu, BPC-157, TB-500 and KPV — combining skin, tissue-repair and anti-inflammatory signalling in a single draw.

An average dose looks like:

80 mg vial + 2 mL water = 40,000 mcg/mL
4 mg → 0.10 mL  ·  10 units

See the full profile →

04SemaglutideMetabolic
What people use it for

Substantial weight loss (often 10–15%+ of body weight); strong appetite suppression; reduced “food noise”; improved blood sugar and metabolic markers; better energy/mobility after weight loss.

Researched for

GLP-1 receptor agonist. The most clinically validated peptide here — large randomised trials for glycaemic control and weight.

An average dose looks like:

5 mg vial + 1 mL water = 5,000 mcg/mL
1 mg → 0.20 mL  ·  20 units

Read the deep dive →

See the full profile →

05RetatrutideMetabolic
What people use it for

Rapid and large-scale weight loss; strong visceral and liver fat reduction; clean energy rather than fatigue; solid appetite control. Often described as stronger than prior GLP-1s.

Researched for

Investigational triple agonist — GLP-1, GIP and glucagon receptors at once. Phase 2 figures are the largest in the class so far.

An average dose looks like:

10 mg vial + 2 mL water = 5,000 mcg/mL
1 mg → 0.20 mL  ·  20 units

See the full profile →

06MOTS-cMetabolic
What people use it for

More even daily energy; better exercise recovery and endurance; improved metabolic “feel” (including modest fasting glucose improvements in some); cleaner energy utilization.

Researched for

A peptide encoded inside mitochondrial DNA, studied as an exercise-mimetic signal tied to energy use and insulin sensitivity.

An average dose looks like:

10 mg vial + 2 mL water = 5,000 mcg/mL
2.5 mg → 0.50 mL  ·  50 units

See the full profile →

07NAD+Cellular energy
What people use it for

Higher energy levels; reduced fatigue; sharper mental clarity and focus; improved mood or motivation; general sense of feeling more youthful or recovered (especially injectable/IV forms).

Researched for

A coenzyme central to cellular energy and DNA repair. Its age-related decline anchors much of modern longevity research.

An average dose looks like:

1000 mg vial + 8 mL water = 125,000 mcg/mL
50 mg → 0.40 mL  ·  40 units

Read the deep dive →

See the full profile →

08SemaxFocus
What people use it for

Enhanced focus, working memory, verbal fluency, and mental clarity; neuroprotective-like effects; often described as a clean cognitive boost without heavy stimulation.

Researched for

Derived from ACTH; developed in Russia and used there in neurology. Studied for focus, memory and neuroprotection via BDNF.

An average dose looks like:

10 mg vial + 2 mL water = 5,000 mcg/mL
500 mcg → 0.10 mL  ·  10 units

See the full profile →

09CJC-1295 + IpamorelinGrowth hormone
What people use it for

Deeper, more restorative sleep (often earliest effect); better workout recovery; gradual improvements in body composition (lean mass gains, fat loss); modest energy or skin quality gains.

Researched for

A GHRH analogue plus a selective ghrelin-receptor agonist, studied together for a fuller natural GH pulse.

Read the deep dive →

See the full profile →

10GHK-CuSkin
What people use it for

Improved skin firmness, elasticity, and collagen production; reduced fine lines/wrinkles; better wound healing; clearer skin tone; sometimes thicker hair or faster tissue recovery.

Researched for

Collagen and elastin synthesis, skin firmness, tissue regeneration. The human clinical evidence is TOPICAL, not injected.

See the full profile →

11TirzepatideMetabolic
What people use it for

Large weight loss (trial averages around 15–20% of body weight at the top doses); strong appetite suppression and reduced “food noise”; better blood sugar and insulin sensitivity; often reported as easier on the stomach than semaglutide for the same result.

Researched for

Dual GIP and GLP-1 receptor agonist. Approved as Mounjaro (type 2 diabetes) and Zepbound (obesity), with large trial data behind both. A prescription medicine, not a research compound, wherever it is approved.

See the full profile →

12BPC-157 + TB-500Recovery
What people use it for

The two repair peptides in one draw: tendon, ligament and muscle recovery, plus the gut-settling and anti-inflammatory effects people attribute to BPC-157, without running two vials and two injections.

Researched for

The two most-referenced tissue-repair research peptides, co-supplied in one vial, usually in equal amounts. Each has its own animal literature; the combination itself has essentially none.

BPC-157 profile →

TB-500 profile →

13TesamorelinBody composition
What people use it for

Meaningful reductions in visceral abdominal fat; modest gains in lean muscle area/density; smaller waist circumference; improved body composition.

Researched for

A stabilised GHRH analogue. The only compound on this list FDA-approved for a body-composition indication.

See the full profile →

14EpithalonLongevity
What people use it for

Better sleep quality (deeper, more restorative); more vivid dreams; subtle lift in daytime energy/vitality; occasional reports of improved skin or overall “reset” feeling after short cycles.

Researched for

A four-amino-acid peptide from Russian gerontology, proposed to activate telomerase.

Read the deep dive →

See the full profile →

15GLOWSkin & recovery
What people use it for

Skin quality, tissue repair and recovery from a single injection. The “aesthetic” blend: chosen for firmer skin and faster healing together rather than for any one effect on its own.

Researched for

A three-peptide blend of GHK-Cu, BPC-157 and TB-500 in one vial. KLOW is this plus KPV. No study has tested the combination; whatever evidence exists is borrowed from each component separately.

KLOW profile →

GHK-Cu profile →

165-Amino-1MQMetabolic
What people use it for

Fat loss without appetite suppression; a modest metabolic lift; sometimes paired with a GLP-1 in the hope of protecting muscle. Taken orally as a capsule, not injected.

Researched for

A small-molecule NNMT inhibitor, not a peptide. Studied in cell and mouse models of fat metabolism and fat-cell growth. No human trials at all.

17PT-141Sexual health
What people use it for

Clear increase in sexual desire and arousal in both men and women; often beginning within 45–90 minutes and lasting several hours; can work independently of visual stimulation for some.

Researched for

A melanocortin agonist working through the nervous system rather than blood flow. FDA-approved as Vyleesi.

See the full profile →

18SelankCalm
What people use it for

Reduced baseline anxiety and stress reactivity; calm but non-sedating state; improved emotional stability; better performance under pressure; mild mood elevation for some.

Researched for

Based on the immune fragment tuftsin; developed in Russia as an anxiolytic. Researched for calm and stress resilience.

See the full profile →

19IpamorelinGrowth hormone
What people use it for

Similar profile to the CJC-1295 combo but simpler dosing and a smaller reconstitution volume: better sleep, workout recovery, gradual lean-mass and fat-composition change.

Researched for

A selective ghrelin-receptor agonist and GH secretagogue — the same peptide in the CJC-1295 blend, but also used alone. Raises GH without meaningfully raising cortisol or prolactin.

Read the deep dive →

See the full profile →

20Melanotan 2Pigmentation
What people use it for

Rapid tanning with less UV exposure; increased libido and sexual arousal (including spontaneous erections in men); mild appetite suppression alongside skin-darkening effects.

Researched for

A melanocortin agonist that signals the skin to produce more melanin from less UV exposure.

See the full profile →

21SS-31Mitochondrial
What people use it for

Improved mitochondrial energy production; reduced fatigue; better exercise tolerance or muscle function (more pronounced with mitochondrial issues); cleaner energy feel. Results more mixed in healthy users.

Researched for

Also called elamipretide. Targets cardiolipin in the mitochondrial membrane; FDA-approved for a rare genetic disease.

See the full profile →

22KPVGut & skin
What people use it for

Anti-inflammatory effects; reduced gut discomfort and bloating; calmer inflammatory bowel or mast-cell-related symptoms; general settling of systemic inflammation.

Researched for

The active C-terminal fragment of α-MSH — anti-inflammatory signalling across gut, skin and immune tissue.

See the full profile →

23Kisspeptin-10Sexual health
What people use it for

Libido and arousal (most often reported by men); a lift in the body’s own testosterone signalling rather than a replacement for it; occasionally used around fertility.

Researched for

A fragment of the hormone that sits upstream of GnRH, and so of LH, FSH and testosterone. Human studies exist, mostly in reproductive endocrinology and brain-imaging work on sexual response. Short-acting.

24DSIPSleep
What people use it for

Improved sleep architecture — easier onset, more deep/slow-wave sleep, fewer nighttime awakenings, and feeling more refreshed — without next-day hangover of many sedatives.

Researched for

Delta sleep-inducing peptide — studied for deep delta-wave sleep activity.

See the full profile →

25Thymosin Alpha-1Immune
What people use it for

Immune support: fewer or shorter infections; used through illness recovery; sometimes in autoimmune, long-COVID or chronic-fatigue contexts; a general sense of resilience.

Researched for

Identical to a natural thymic hormone. Approved as Zadaxin in more than 30 countries for hepatitis B and as a vaccine adjuvant, though not in Canada or the US. One of the longer human trial histories on this list.

26CagrilintideMetabolic
What people use it for

Weight loss by a different route from the GLP-1s: fullness and slower stomach emptying. Most often run alongside semaglutide (the “CagriSema” pairing) for added effect rather than on its own.

Researched for

A long-acting amylin analogue. Phase 2 and phase 3 trials, mostly in combination with semaglutide as CagriSema. Investigational: approved nowhere yet.

Semaglutide profile →

27AOD-9604Fat loss
What people use it for

Fat loss, particularly stubborn abdominal fat, without the appetite effects of a GLP-1; sometimes for joint or cartilage support. Effects, where reported, are described as subtle.

Researched for

The fat-metabolism fragment of growth hormone (residues 176–191), with the growth-promoting part removed. Went through human obesity trials in the 2000s and failed to show meaningful weight loss. The joint-repair line is preclinical.

28IGF-1 LR3Growth
What people use it for

Increased muscle fullness and pumps; faster recovery; modest lean-mass gains; better nutrient partitioning; improved training output when timed around workouts and carbohydrates.

Researched for

A long-acting IGF-1 analogue — the growth factor downstream of growth hormone.

See the full profile →

29SLU-PP-332Exercise mimetic
What people use it for

“Exercise in a pill”: endurance, fat oxidation and energy, taken orally. Very new, and the reports are thin.

Researched for

A small-molecule ERR agonist, not a peptide. Mouse studies only: more endurance and more fat burned with no change in activity. No human data of any kind.

30GlutathioneAntioxidant
What people use it for

Skin brightening (a major driver of injectable and IV use); liver support and “detox”; recovery from illness or hard training; a general antioxidant reset.

Researched for

The body’s principal intracellular antioxidant. Decades of clinical use as an IV drug in some countries; the skin-lightening evidence is a handful of small, short trials. Oral absorption is poor, which is why people inject it.

31SermorelinGrowth hormone
What people use it for

Improved sleep quality; better recovery; increased energy and vitality; gradual lean-mass gains; reductions in body fat (especially visceral) with consistent use.

Researched for

A GHRH analogue and one of the longest-standing tools in growth-hormone research.

See the full profile →

Read this before using any figure above

A dose shown here is one person's, not a standard. Where an "average dose looks like" figure appears, it's from real personal experience at that reconstitution — not a community average, not a clinical dose, and not necessarily right for anyone else's body, goals, or product.

Most compounds are intentionally blank. That's not a gap to fill later with a guessed range — it means there's no personal reference to give, and we'd rather say nothing than imply confidence that isn't there.

The volume depends entirely on the reconstitution shown. Different vial size or water volume changes the draw — the calculator will do that math for any combination.

Researched for and used for are different things, and the gap between them is the useful part. GHK-Cu's human evidence is topical while people inject it. Tesamorelin is approved for HIV-associated lipodystrophy, not general fat loss.

Nothing here is medical advice. Several of these are prescription medicines in Canada and the US, and several are approved nowhere at all.

For education only · Not medical adviceSourced clean · Documented in full