A coenzyme central to cellular energy and DNA repair. Its age-related decline anchors much of modern longevity research.
Higher energy levels; reduced fatigue; sharper mental clarity and focus; improved mood or motivation; general sense of feeling more youthful or recovered (especially injectable/IV forms).
A coenzyme rather than a peptide, and the tier depends entirely on which molecule and which route. The oral precursors NMN and NR have dozens of randomised trials behind them and are licensed natural health products in Canada. Injected NAD+ has no outcomes trial at all: a 2026 systematic review of 113 studies found none for IV or IM NAD+ in anti-ageing or wellness use. Clinic IV use is widespread but thinly evidenced, and IV doses do not transfer to a subcutaneous syringe.
An average dose looks like:
1000 mg vial + 8 mL water = 125,000 mcg/mL
50 mg → 0.40 mL · 40 units
That figure is one person’s at that exact reconstitution — not a community average, not a clinical dose. A different vial size or water volume changes the draw entirely.
| NAD+ | 3 mL water | 5 mL water | 8 mL water |
|---|---|---|---|
| 1000 mg vial | 333,333 mcg/mL | 200,000 mcg/mL | 125,000 mcg/mL |
| One unit (0.01 mL) | 3,333 mcg | 2,000 mcg | 1,250 mcg |
Concentration = vial contents ÷ water added. It is the same compound at every volume — more water only means a weaker solution, larger syringe marks that are easier to read, and a larger injection volume. On a standard U-100 insulin syringe, one unit is 0.01 mL at any barrel size.
Education only. This page is educational. Most compounds referenced are not approved for human use, and a "research use only" label carries no legal status of its own.
Reported, not established. Any figure shown is a reported personal reference at the reconstitution stated — not a community average, not a clinical dose, and not necessarily right for anyone else's body, goals, or product.
Blank is deliberate. Where no figure appears, there is no personal reference to give. We would rather say nothing than imply confidence that isn't there.
Not medical advice. Nothing here constitutes medical advice, diagnosis, or treatment. Several of these are prescription medicines in Canada and the US, and several are approved nowhere at all. Consult a qualified healthcare professional before beginning any protocol.