GLP-1 receptor agonist. The most clinically validated peptide here — large randomised trials for glycaemic control and weight.
Substantial weight loss (often 10–15%+ of body weight); strong appetite suppression; reduced “food noise”; improved blood sugar and metabolic markers; better energy/mobility after weight loss.
The most clinically validated compound on this site. Approved as Ozempic (type 2 diabetes) and Wegovy (chronic weight management), backed by large randomised trials. Oral forms exist too: Rybelsus tablets, and an oral Wegovy approved in December 2025. Generic semaglutide has been authorised in Canada since April 2026, the first G7 country to do so. Compounded semaglutide is a different supply route from the approved product.
An average dose looks like:
5 mg vial + 1 mL water = 5,000 mcg/mL
1 mg → 0.20 mL · 20 units
That figure is one person’s at that exact reconstitution — not a community average, not a clinical dose. A different vial size or water volume changes the draw entirely.
| Semaglutide | 1 mL water | 2 mL water | 3 mL water | 5 mL water |
|---|---|---|---|---|
| 5 mg vial | 5,000 mcg/mL | 2,500 mcg/mL | 1,667 mcg/mL | 1,000 mcg/mL |
| One unit (0.01 mL) | 50 mcg | 25 mcg | 17 mcg | 10 mcg |
Concentration = vial contents ÷ water added. It is the same compound at every volume — more water only means a weaker solution, larger syringe marks that are easier to read, and a larger injection volume. On a standard U-100 insulin syringe, one unit is 0.01 mL at any barrel size.
Education only. This page is educational. Most compounds referenced are not approved for human use, and a "research use only" label carries no legal status of its own.
Reported, not established. Any figure shown is a reported personal reference at the reconstitution stated — not a community average, not a clinical dose, and not necessarily right for anyone else's body, goals, or product.
Blank is deliberate. Where no figure appears, there is no personal reference to give. We would rather say nothing than imply confidence that isn't there.
Not medical advice. Nothing here constitutes medical advice, diagnosis, or treatment. Several of these are prescription medicines in Canada and the US, and several are approved nowhere at all. Consult a qualified healthcare professional before beginning any protocol.